Introduction Cyclodextrins (CD) are a class of cyclic oligosacchariders that have a hydrophobic molecule-sized cavity (Del Valle, 2004). The most common CDs are toroidally (‘trash -can’) shaped polysaccharides composed of 6, 7, or 8 D-glucopyranoside units joined by a 1,4-glycosidic link; and are referred to as α-, β- and γ-cyclodextrin,